Optimized and Scalable Green Extraction of Pristimerin, an Anticancerigen from Mortonia greggii, by Ethanol–Phosphate Aqueous Two-Phase Systems

The natural triterpene pristimerin possesses interesting potential against several types of cancer. However, its production at the industrial level requires novel environmentally friendly and efficient extraction procedures. Here, we analyze an ethanol–phosphate aqueous two-phase system and the effect of its design parameters such as the tie-line length (TLL) and volume ratio (VR), on the direct extraction of pristimerin. The results showed that...