Insulin-induced changes in skeletal muscle microvascular perfusion are dependent upon perivascular adipose tissue in women
Abstract
Obesity increases the risk of cardiovascular disease and type 2 diabetes, partly through reduced insulin-induced microvascular vasodilation, which causes impairment of glucose delivery and uptake. We studied whether perivascular adipose tissue (PVAT) controls insulin-induced vasodilation in human muscle, and whether altered properties of PVAT relate to reduced insulin-induced vasodilation in obesity.Insulin-induced microvascular recruitment was...
Paper Details
Title
Insulin-induced changes in skeletal muscle microvascular perfusion are dependent upon perivascular adipose tissue in women
Published Date
May 24, 2015
Journal
Volume
58
Issue
8
Pages
1907 - 1915
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