Appropriate expression of P57kip2 drives trophoblast fusion via cell cycle arrest
Abstract
The syncytiotrophoblast, derived from cytotrophoblast fusion, is responsible for maternal-fetal exchanges, secretion of pregnancy-related hormones, and fetal defense against pathogens. Inadequate cytotrophoblast fusion can lead to pregnancy disorders, such as preeclampsia and fetal growth restriction. However, little is known about the mechanism of cytotrophoblast fusion in both physiological and pathological pregnancy conditions. In this study,...
Paper Details
Title
Appropriate expression of P57kip2 drives trophoblast fusion via cell cycle arrest
Published Date
Jun 1, 2021
Journal
Volume
161
Issue
6
Pages
633 - 644
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