Voxel‐level Classification of Prostate Cancer on Magnetic Resonance Imaging: Improving Accuracy Using Four‐Compartment Restriction Spectrum Imaging

Background Diffusion magnetic resonance imaging (MRI) is integral to detection of prostate cancer (PCa), but conventional apparent diffusion coefficient (ADC) cannot capture the complexity of prostate tissues and tends to yield noisy images that do not distinctly highlight cancer. A four‐compartment restriction spectrum imaging (RSI 4 ) model was recently found to optimally characterize pelvic diffusion signals, and the model coefficient for the...