Nascent Prostate Cancer Heterogeneity Drives Evolution and Resistance to Intense Hormonal Therapy

Volume: 80, Issue: 6, Pages: 746 - 757
Published: Dec 1, 2021
Abstract
Patients diagnosed with high risk localized prostate cancer have variable outcomes following surgery. Trials of intense neoadjuvant androgen deprivation therapy (NADT) have shown lower rates of recurrence among patients with minimal residual disease after treatment. The molecular features that distinguish exceptional responders from poor responders are not known. To identify genomic and histologic features associated with treatment resistance at...
Paper Details
Title
Nascent Prostate Cancer Heterogeneity Drives Evolution and Resistance to Intense Hormonal Therapy
Published Date
Dec 1, 2021
Volume
80
Issue
6
Pages
746 - 757
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