Solubility and Model Correlation of Doxofylline in Pure Solvents at the Temperature Range of 283.15–323.15 K

Volume: 66, Issue: 5, Pages: 2034 - 2049
Published: Apr 2, 2021
Abstract
Doxofylline (DFL) is a theophylline derivative with poor solubility in water. In this paper, the solubility of DFL (as mole fraction) in 17 organic solvents including 4 esters (ethyl acetate, n-propyl acetate, n-butyl acetate, methyl propionate), 8 alcohols (methanol, ethanol, n-propanol, iso-propanol, n-butanol, iso-butanol, sec-butanol, n-pentanol), 3 ketones (acetone, 2-butanone, cyclohexanone), acetonitrile, and water was studied at the...
Paper Details
Title
Solubility and Model Correlation of Doxofylline in Pure Solvents at the Temperature Range of 283.15–323.15 K
Published Date
Apr 2, 2021
Volume
66
Issue
5
Pages
2034 - 2049
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