Substantial anti-gout effect conferred by common and rare dysfunctional variants of URAT1/SLC22A12

Volume: 60, Issue: 11, Pages: 5224 - 5232
Published: Apr 2, 2021
Abstract
Gout, caused by chronic elevation of serum uric acid levels, is the commonest form of inflammatory arthritis. The causative effect of common and rare variants of ATP-binding cassette transporter G2 (ABCG2/BCRP) on gout risk has been studied, but little attention has been paid to the effect of common (rs121907892, p.W258X) and rare variants of urate transporter 1 (URAT1/SLC22A12) on gout, despite dysfunctional variants of URAT1 having been...
Paper Details
Title
Substantial anti-gout effect conferred by common and rare dysfunctional variants of URAT1/SLC22A12
Published Date
Apr 2, 2021
Volume
60
Issue
11
Pages
5224 - 5232
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