Magnesium-based biomaterials as emerging agents for bone repair and regeneration: from mechanism to application

Magnesium (Mg) is the fourth most abundant element in the human body and is important in terms of specific osteogenesis functions. Here, we provide a comprehensive review of the use of magnesium-based biomaterials (MBs) in bone reconstruction. We review the history of MBs and their excellent biocompatibility, biodegradability and osteopromotive properties, highlighting them as candidates for a new generation of biodegradable orthopedic implants....