Inhibition of NOX1 Mitigates Blood Pressure Increases in Elastin Insufficiency

Volume: 2, Issue: 3
Published: Mar 15, 2021
Abstract
Elastin (ELN) insufficiency leads to the cardiovascular hallmarks of the contiguous gene deletion disorder, Williams–Beuren syndrome, including hypertension and vascular stiffness. Previous studies showed that Williams–Beuren syndrome deletions, which extended to include the NCF1 gene, were associated with lower blood pressure (BP) and reduced vascular stiffness. NCF1 encodes for p47phox, the regulatory component of the NOX1 NADPH oxidase...
Paper Details
Title
Inhibition of NOX1 Mitigates Blood Pressure Increases in Elastin Insufficiency
Published Date
Mar 15, 2021
Journal
Volume
2
Issue
3
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