The Inherited and Familial Component of Early-Onset Colorectal Cancer

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Volume: 10, Issue: 3, Pages: 710 - 710
Published: Mar 23, 2021
Abstract
Early-onset colorectal cancer (EOCRC), defined as that diagnosed before the age of 50, accounts for 10–12% of all new colorectal cancer (CRC) diagnoses. Epidemiological data indicate that EOCRC incidence is increasing, despite the observed heterogeneity among countries. Although the cause for such increase remains obscure, ≈13% (range: 9–26%) of EOCRC patients carry pathogenic germline variants in known cancer predisposition genes, including...
Paper Details
Title
The Inherited and Familial Component of Early-Onset Colorectal Cancer
Published Date
Mar 23, 2021
Journal
Volume
10
Issue
3
Pages
710 - 710
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