CTLA-2 Alpha Is a Potent Inhibitor of Angiogenesis in Murine Ocular Tissue
Abstract
Cytotoxic T lymphocyte antigen-2 (CTLA-2) alpha has been reported to suppress the activities of cathepsin L (Cath L), which is deeply involved in angiogenesis. Therefore, we assessed whether CTLA-2 alpha plays a role in angiogenesis in ocular tissue. To establish models of corneal inflammation and experimental choroidal neovascularization (CNV), male C57BL/6J mice (n = 5) underwent corneal suture placement or laser-induced CNV, respectively....
Paper Details
Title
CTLA-2 Alpha Is a Potent Inhibitor of Angiogenesis in Murine Ocular Tissue
Published Date
Mar 15, 2021
Journal
Volume
10
Issue
3
Pages
456 - 456
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