Cardiac macrophages prevent sudden death during heart stress

Volume: 12, Issue: 1
Published: Mar 26, 2021
Abstract
Cardiac arrhythmias are a primary contributor to sudden cardiac death, a major unmet medical need. Because right ventricular (RV) dysfunction increases the risk for sudden cardiac death, we examined responses to RV stress in mice. Among immune cells accumulated in the RV after pressure overload-induced by pulmonary artery banding, interfering with macrophages caused sudden death from severe arrhythmias. We show that cardiac macrophages crucially...
Paper Details
Title
Cardiac macrophages prevent sudden death during heart stress
Published Date
Mar 26, 2021
Volume
12
Issue
1
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