Low Immunogenicity and Immunosuppressive Properties of Human ESC- and iPSC-Derived Retinas
Abstract
ESC- and iPSC-derived retinal transplantation is a promising therapeutic approach for disease with end-stage retinal degeneration, such as retinitis pigmentosa and age-related macular degeneration. We previously showed medium- to long-term survival, maturation, and light response of transplanted human ESC- and iPSC-retina in mouse, rat, and monkey models of end-stage retinal degeneration. Because the use of patient hiPSC-derived retina with a...
Paper Details
Title
Low Immunogenicity and Immunosuppressive Properties of Human ESC- and iPSC-Derived Retinas
Published Date
Apr 1, 2021
Journal
Volume
16
Issue
4
Pages
851 - 867
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Notes
History