Adaptive immunity to human coronaviruses is widespread but low in magnitude
Abstract
Endemic human coronaviruses (hCoVs) circulate worldwide but cause minimal mortality. Although seroconversion to hCoV is near ubiquitous during childhood, little is known about hCoV-specific T-cell memory in adults.We quantified CD4 T-cell and antibody responses to hCoV spike antigens in 42 SARS-CoV-2-uninfected individuals. Antigen-specific memory T cells and circulating T follicular helper (cTFH) cells were identified using an...
Paper Details
Title
Adaptive immunity to human coronaviruses is widespread but low in magnitude
Published Date
Jan 1, 2021
Volume
10
Issue
3
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