Slc20a1b is essential for hematopoietic stem/progenitor cell expansion in zebrafish
Abstract
Hematopoietic stem and progenitor cells (HSPCs) are able to self-renew and can give rise to all blood lineages throughout their lifetime, yet the mechanisms regulating HSPC development have yet to be discovered. In this study, we characterized a hematopoiesis defective zebrafish mutant line named smu07, which was obtained from our previous forward genetic screening, and found the HSPC expansion deficiency in the mutant. Positional cloning...
Paper Details
Title
Slc20a1b is essential for hematopoietic stem/progenitor cell expansion in zebrafish
Published Date
Mar 16, 2021
Journal
Volume
64
Issue
12
Pages
2186 - 2201
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