Glycomics

Glycan

Glycosylation

Biology

Gene

Glycoprotein

HEK 293 cells

Computational biology

Cell biology

Biochemistry

Gene knockout

Developmental Cell

Diverse glycan structures are synthesized depending on cell types. Huang et al. have developed a comprehensive glycosylation mapping tool based on gene expression, named GlycoMaple, for visualizing glycosylation pathways and estimating glycan structures synthesized in cells. The tool could contribute to supporting glycan analysis, biomarker development, and glycoengineering.

Global mapping of glycosylation pathways in human-derived cells