Polysaccharide-Rich Red Algae (Gelidium amansii) Hot-Water Extracts Ameliorate the Altered Plasma Cholesterol and Hepatic Lipid Homeostasis in High-Fat Diet-Fed Rats

We have demonstrated that red algae Gelidium amansii (GA) hot-water extract (GHE) is a polysaccharide-rich fraction, containing 68.54% water-soluble indigestible carbohydrate polymers; the molecular weight of major polysaccharide is 892. Here, we investigated the mechanisms of GHE on plasma and hepatic lipid metabolisms in high-fat (HF) diet-fed rats. Rats were divided into: normal diet group, HF-diet group, HF-diet+5% GHE group, and HF-diet+1%...