Chemical induction of neurogenic properties in mammalian Müller glia

Volume: 39, Issue: 8, Pages: 1081 - 1090
Published: Mar 25, 2021
Abstract
Müller glia (MG), cells that maintain homeostasis in the retina, are dormant stem cells that can regenerate neurons upon injury. However, the regenerative property of MG, which is reproducibly displayed in the lower vertebrates, is not readily observed in the mammals even upon forced expression of regulatory genes or exposure to growth factors. Here, we demonstrate a reproducible unmasking of the neurogenic properties of enriched rodent MG by...
Paper Details
Title
Chemical induction of neurogenic properties in mammalian Müller glia
Published Date
Mar 25, 2021
Journal
Volume
39
Issue
8
Pages
1081 - 1090
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