Histologic evidence for a humoral immune response in synovitis associated with cranial cruciate ligament disease in dogs

Objective To investigate histopathological features of synovium from dogs with cranial cruciate ligament disease (CCLD) to seek mechanisms of osteoarthritis (OA) associated with CCLD. Study design Retrospective, single‐institution case series. Animals Thirty client‐owned dogs. Methods Synovial biopsies (n = 30) obtained from stifles with CCLD were assessed by using two synovitis histopathology grading systems (Krenn and Hospital for Special...