Computationally guided high-throughput design of self-assembling drug nanoparticles
Abstract
Nanoformulations of therapeutic drugs are transforming our ability to effectively deliver and treat a myriad of conditions. Often, however, they are complex to produce and exhibit low drug loading, except for nanoparticles formed via co-assembly of drugs and small molecular dyes, which display drug-loading capacities of up to 95%. There is currently no understanding of which of the millions of small-molecule combinations can result in the...
Paper Details
Title
Computationally guided high-throughput design of self-assembling drug nanoparticles
Published Date
Mar 25, 2021
Journal
Volume
16
Issue
6
Pages
725 - 733
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Notes
History