Immunotherapy use outside clinical trial populations: never say never?
Abstract
Based on favourable outcomes in clinical trials, immune checkpoint inhibitors (ICIs), most notably programmed cell death protein 1 (PD-1) and cytotoxic T-lymphocyte antigen-4 (CTLA-4) inhibitors, are now widely used across multiple cancer types. However, due to their strict inclusion and exclusion criteria, clinical studies often do not address challenges presented by non-trial populations.This review summarises available data on the efficacy...
Paper Details
Title
Immunotherapy use outside clinical trial populations: never say never?
Published Date
Jul 1, 2021
Journal
Volume
32
Issue
7
Pages
866 - 880
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