Loss of bone morphogenetic protein-binding endothelial regulator causes insulin resistance
Abstract
Accumulating evidence suggests that chronic inflammation of metabolic tissues plays a causal role in obesity-induced insulin resistance. Yet, how specific endothelial factors impact metabolic tissues remains undefined. Bone morphogenetic protein (BMP)–binding endothelial regulator (BMPER) adapts endothelial cells to inflammatory stress in diverse organ microenvironments. Here, we demonstrate that BMPER is a driver of insulin sensitivity. Both...
Paper Details
Title
Loss of bone morphogenetic protein-binding endothelial regulator causes insulin resistance
Published Date
Mar 26, 2021
Journal
Volume
12
Issue
1
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