Engineering the early bone metastatic niche through human vascularized immuno bone minitissues

Volume: 13, Issue: 3, Pages: 035036 - 035036
Published: Apr 26, 2021
Abstract
Bone metastases occur in 65%-80% advanced breast cancer patients. Although significant progresses have been made in understanding the biological mechanisms driving the bone metastatic cascade, traditional 2Din vitromodels and animal studies are not effectively reproducing breast cancer cells (CCs) interactions with the bone microenvironment and suffer from species-specific differences, respectively. Moreover, simplifiedin vitromodels cannot...
Paper Details
Title
Engineering the early bone metastatic niche through human vascularized immuno bone minitissues
Published Date
Apr 26, 2021
Volume
13
Issue
3
Pages
035036 - 035036
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