In Silico Plasma Protein Binding Studies of Selected Group of Drugs Using TLC and HPLC Retention Data
Abstract
Plasma protein binding is an important determinant of the pharmacokinetic properties of chemical compounds in living organisms. The aim of the present study was to determine the index of protein binding affinity based on chromatographic experiments. The question is which chromatographic environment will best mimic the drug–protein binding conditions. Retention data from normal phase thin-layer liquid chromatography (NP TLC), reversed phase (RP)...
Paper Details
Title
In Silico Plasma Protein Binding Studies of Selected Group of Drugs Using TLC and HPLC Retention Data
Published Date
Feb 28, 2021
Journal
Volume
14
Issue
3
Pages
202 - 202
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