Super-resolution mapping of cellular double-strand break resection complexes during homologous recombination
Volume: 118, Issue: 11
Published: Mar 11, 2021
Abstract
Homologous recombination (HR) is a major pathway for repair of DNA double-strand breaks (DSBs). The initial step that drives the HR process is resection of DNA at the DSB, during which a multitude of nucleases, mediators, and signaling proteins accumulates at the damage foci in a manner that remains elusive. Using single-molecule localization super-resolution (SR) imaging assays, we specifically visualize the spatiotemporal behavior of key...
Paper Details
Title
Super-resolution mapping of cellular double-strand break resection complexes during homologous recombination
Published Date
Mar 11, 2021
Volume
118
Issue
11
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