Photoacoustic stimulation with single neuron precision

Published on Mar 5, 2021
· DOI :10.1117/12.2578734
Linli Shi1
Estimated H-index: 1
(BU: Boston University),
Ying Jiang4
Estimated H-index: 4
(BU: Boston University)
+ 1 AuthorsChen Yang74
Estimated H-index: 74
(BU: Boston University)
Source
Abstract
Towards non-genetic, precise neural stimulation, we develop a photoacoustic neural stimulation technology. It employs a fiber-based optoacoustic process, in which pulsed light is delivered through an optical fiber into an absorbing layer coated at the tip, resulting in transient heating and generating a localized acoustic wave. We report photoacoustic stimulation in vitro and in vivo through a lab-built fiber based optoacoustic emitter (FOE). Single neuron optoacoustic neural modulation is achieved through a tapered FOE (TFOE) developed with negligible thermal deposition. TFOE single neuron stimulation is shown to be compatible with patch and provides insights towards mechanical modulation of neural systems.
References0
Newest
Cited By0
Newest
This website uses cookies.
We use cookies to improve your online experience. By continuing to use our website we assume you agree to the placement of these cookies.
To learn more, you can find in our Privacy Policy.