X Chromosome Contribution to the Genetic Architecture of Primary Biliary Cholangitis
Abstract
Background & Aims Genome-wide association studies in primary biliary cholangitis (PBC) have failed to find X chromosome (chrX) variants associated with the disease. Here, we specifically explore the chrX contribution to PBC, a sexually dimorphic complex autoimmune disease. Methods We performed a chrX-wide association study, including genotype data from 5 genome-wide association studies (from Italy, United Kingdom, Canada, China, and Japan; 5244...
Paper Details
Title
X Chromosome Contribution to the Genetic Architecture of Primary Biliary Cholangitis
Published Date
Jun 1, 2021
Journal
Volume
160
Issue
7
Pages
2483 - 2495.e26
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