Targeting receptor-ligand chemistry for drug delivery across blood-brain barrier in brain diseases

Volume: 274, Pages: 119326 - 119326
Published: Jun 1, 2021
Abstract
The blood-brain barrier (BBB) is composed of a layer of endothelial cells that is interspersed with a series of tight junctions and characterized by the absence of fenestrations. The permeability of this barrier is controlled by junctions such as tight junctions and adherent junctions as well as several cells such as astrocytes, pericytes, vascular endothelial cells, neurons, microglia, and efflux transporters with relatively enhanced...
Paper Details
Title
Targeting receptor-ligand chemistry for drug delivery across blood-brain barrier in brain diseases
Published Date
Jun 1, 2021
Volume
274
Pages
119326 - 119326
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