Epidermal graft encourages wound healing by down‐regulation of gap junctional protein and activation of wound bed without graft integration as opposed to split‐thickness skin graft

Wound coverage by split‐thickness skin graft (SSG) and epidermal graft (EG) shortens healing time, with comparable outcomes. However, the healing mechanism of EG is not as well understood as SSG. The difference in the healing mechanisms of EG and SSG was investigated using gap junctional proteins, proliferative marker, and cytokeratin markers. Paired punch biopsies were taken from the wound edge and wound bed from patients undergoing EG and SSG...