Matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in kidney disease
Abstract
Matrix metalloproteinases (MMPs) are a group of zinc and calcium endopeptidases which cleave extracellular matrix (ECM) proteins. They are also involved in the degradation of cell surface components and regulate multiple cellular processes, cell to cell interactions, cell proliferation, and cell signaling pathways. MMPs function in close interaction with the endogenous tissue inhibitors of matrix metalloproteinases (TIMPs), both of which...
Paper Details
Title
Matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in kidney disease
Published Date
Jan 1, 2021
Journal
Pages
141 - 212
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Notes
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