Streamlining CRISPR spacer-based bacterial host predictions to decipher the viral dark matter
Abstract
Thousands of new phages have recently been discovered thanks to viral metagenomics. These phages are extremely diverse and their genome sequences often do not resemble any known phages. To appreciate their ecological impact, it is important to determine their bacterial hosts. CRISPR spacers can be used to predict hosts of unknown phages, as spacers represent biological records of past phage–bacteria interactions. However, no guidelines have been...
Paper Details
Title
Streamlining CRISPR spacer-based bacterial host predictions to decipher the viral dark matter
Published Date
Mar 2, 2021
Journal
Volume
49
Issue
6
Pages
3127 - 3138
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