<em>In silico</em> drug-protein binding studies using TLC retention data

Protein binding (PB) is one of the most important factors influencing the transport and distribution of a drug in a living organism. The ability to create such connections and their durability determine the bioavailability of drugs at the site of binding to a biological target, penetration through the body natural protective barriers, drug toxicity and elimination. In addition to in vitro studies, drug-protein binding analysis uses different...