Levofloxacin and sulfa drugs linked via Schiff bases: Exploring their urease inhibition, enzyme kinetics and in silico studies
Abstract
Involvement of urease in various pathological conditions specifically in gastric and peptic ulcers make it an important therapeutic target. In the present study urease inhibition was investigated by newly designed Schiff bases of levofloxacin. Structure elucidation of these compounds were done by spectral studies such as IR, 1H NMR and 13C NMR and elemental analysis. In vitro urease enzyme inhibition assay revealed the compounds LS01, LS06 and...
Paper Details
Title
Levofloxacin and sulfa drugs linked via Schiff bases: Exploring their urease inhibition, enzyme kinetics and in silico studies
Published Date
Jul 1, 2021
Volume
1235
Pages
130226 - 130226
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