Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight

Published on Mar 9, 2021in eLife7.08
· DOI :10.7554/ELIFE.60060
Maria Lc Iurilli1
Estimated H-index: 1
(Imperial College London),
Bin Zhou26
Estimated H-index: 26
(Imperial College London)
+ 1378 AuthorsSarah Filippi20
Estimated H-index: 20
(Imperial College London)
Sources
Abstract
From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia and sub-Saharan Africa, the underweight tail of the BMI distribution was left behind as the distribution shifted. There is a need for policies that address all forms of malnutrition by making healthy foods accessible and affordable, while restricting unhealthy foods through fiscal and regulatory restrictions.
References63
Newest
#2Bin ZhouH-Index: 26
Last. Majid EzzatiH-Index: 138
view all 1362 authors...
Summary Background Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. Methods For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease Risk Factor Collaboration. We applied a Baye...
31 CitationsSource
#1Corinna Hawkes (City University London)H-Index: 60
#2Marie T. Ruel (IFPRI: International Food Policy Research Institute)H-Index: 80
Last. Francesco Branca (WHO: World Health Organization)H-Index: 34
view all 5 authors...
Actions to address different forms of malnutrition are typically managed by separate communities, policies, programmes, governance structures, and funding streams. In contrast, double duty actions, which aim to simultaneously tackle both undernutrition and problems of overweight, obesity and diet-related non-communicable diseases (DR-NCDs) have been proposed as a way to effectively address malnutrition in all its forms in a more holsitic way. This paper identifies ten double duty actions that ha...
103 CitationsSource
#2Ana Lydia Sawaya (UNIFESP: Federal University of São Paulo)H-Index: 32
Last. Alessandro R DemaioH-Index: 18
view all 7 authors...
Summary Malnutrition has historically been researched and addressed within two distinct silos, focusing either on undernutrition, food insecurity, and micronutrient deficiencies, or on overweight, obesity, and dietary excess. However, through rapid global nutrition transition, an increasing proportion of individuals are exposed to different forms of malnutrition during the life course and have the double burden of malnutrition (DBM) directly. Long-lasting effects of malnutrition in early life ca...
122 CitationsSource
#1Barry M. Popkin (UNC: University of North Carolina at Chapel Hill)H-Index: 177
#2Camila Corvalán (University of Chile)H-Index: 26
Last. Laurence M. Grummer-Strawn (WHO: World Health Organization)H-Index: 8
view all 3 authors...
Summary The double burden of malnutrition (DBM), defined as the simultaneous manifestation of both undernutrition and overweight and obesity, affects most low-income and middle-income countries (LMICs). This Series paper describes the dynamics of the DBM in LMICs and how it differs by socioeconomic level. This Series paper shows that the DBM has increased in the poorest LMICs, mainly due to overweight and obesity increases. Indonesia is the largest country with a severe DBM, but many other Asian...
214 CitationsSource
#1Maria Brandkvist (NTNU: Norwegian University of Science and Technology)H-Index: 2
#2Johan Håkon Bjørngaard (NTNU: Norwegian University of Science and Technology)H-Index: 6
Last. Gunnhild Åberge Vie (NTNU: Norwegian University of Science and Technology)H-Index: 8
view all 6 authors...
Abstract Objectives To study the trajectories of body mass index (BMI) in Norway over five decades and to assess the differential influence of the obesogenic environment on BMI according to genetic predisposition. Design Longitudinal study. Setting General population of Nord-Trondelag County, Norway. Participants 118 959 people aged 13-80 years who participated in a longitudinal population based health study (Nord-Trondelag Health Study, HUNT), of whom 67 305 were included in analyses of associa...
37 CitationsSource
#1Honor Bixby (Imperial College London)H-Index: 16
#2James Bentham (UKC: University of Kent)H-Index: 19
Last. Majid Ezzati (Imperial College London)H-Index: 138
view all 51 authors...
Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities1,2. This has led to a widely reported view that urbaniz ...
209 CitationsSource
#1Katia Jakovljevic Pudla Wagner (UFSC: Universidade Federal de Santa Catarina)H-Index: 4
Last. S. V. Subramanian (Harvard University)H-Index: 79
view all 5 authors...
Background Brazil is among the 10 countries with the highest prevalence of overweight in the world. The aim was to analyse the changes in the dispersion of body mass index (BMI) in the Brazilian population from the 1970s to 2013 in specific population groups. Methods Data were extracted from five national household surveys between 1974–1975 and 2013, including adults aged 20 to 64. We calculated SD, median, fifth and 95th percentiles of BMI for each sociodemographic category (sex, age, schooling...
3 CitationsSource
#1Fahad Razak (St. Michael's Hospital)H-Index: 21
#1Fahad Razak (St. Michael's GAA, Sligo)H-Index: 6
Last. Daniel J. Corsi (Ottawa Hospital Research Institute)H-Index: 25
view all 7 authors...
Abstract Objectives To examine whether conditions related to scarcity at the left side of the distribution (anaemia, severe chronic energy deficiency, and underweight) are as strongly related to population means as conditions of excess at the right side of the distribution (overweight and obesity). Design Observational study. Setting 65 countries, with nationally representative cross sectional data from 1994 to 2014 obtained from the Demographic Health Surveys. Participants Non-pregnant women ag...
4 CitationsSource
#1Alexandre Lebel (Laval University)H-Index: 13
#2S. V. Subramanian (Harvard University)H-Index: 79
Last. Fahad Razak (Harvard University)H-Index: 21
view all 5 authors...
Objective Research studying population-level body mass index (BMI) trends document increases in mean or prevalence of overweight/obese but less consideration has been given to describing the changing distribution of BMI. The objective of this research was to perform a detailed analysis of changes in the BMI distribution in Canada.
2 CitationsSource
#1Majid Ezzati (Imperial College London)H-Index: 138
#2Bin Zhou (Imperial College London)H-Index: 26
Last. Julio Zuniga CisnerosH-Index: 10
view all 846 authors...
Background: Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successful clinical interventions to control blood pressure in the hypertensive population). Our aim was to quantify the contributions of these two phenomena to the worldwide trends in the prevalence of raised blood press...
39 CitationsSource
Cited By16
Newest
#1Daniel J. Simpson (Edin.: University of Edinburgh)H-Index: 4
#2Tamir Chandra (Edin.: University of Edinburgh)H-Index: 22
Advanced age is the main common risk factor for cancer, cardiovascular disease and neurodegeneration. Yet, more is known about the molecular basis of any of these groups of diseases than the changes that accompany ageing itself. Progress in molecular ageing research was slow because the tools predicting whether someone aged slowly or fast (biological age) were unreliable. To understand ageing as a risk factor for disease and to develop interventions, the molecular ageing field needed a quantitat...
Source
#1Ryohei Iwata (Allen Institute for Brain Science)
Abstract null null The ontogeny programs are highly conserved across all vertebrates, although there are significant temporal variations in interspecies developmental processes. Changing the timing and rate of developmental processes could affect subsequent organogenesis profoundly and may also have been critical factors in evolutionary diversity. However, despite their potential importance, the cellular and molecular mechanisms that control interspecies differences in developmental timescale re...
Source
#1Beier Yao (MSU: Michigan State University)H-Index: 4
#2Martin Rolfs (Humboldt University of Berlin)H-Index: 28
Last. Katharine N. Thakkar (MSU: Michigan State University)H-Index: 22
view all 9 authors...
Corollary discharge (CD) signals are "copies" of motor signals sent to sensory regions that allow animals to adjust sensory consequences of self-generated actions. Autism spectrum disorder (ASD) is characterized by sensory and motor deficits, which may be underpinned by altered CD signaling. We evaluated oculomotor CD using the blanking task, which measures the influence of saccades on visual perception, in 30 children with ASD and 35 typically developing (TD) children. Participants were instruc...
Source
#1Anne Kathrine Bengaard (Copenhagen University Hospital)H-Index: 1
#2Esben Iversen (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 1
Last. Morten Baltzer Houlind (UCPH: University of Copenhagen)H-Index: 5
view all 9 authors...
AIM To investigate whether the association between levels of medication use (including polypharmacy and potentially inappropriate medications [PIMs]) and health outcomes such as readmission and mortality is dependent on baseline suPAR. METHODS This registry-based cohort study included medical patients admitted to the emergency department (ED) at Copenhagen University Hospital Hvidovre, Denmark. Patients were grouped according to their admission suPAR levels: low (0-3 ng/mL), intermediate (3-6 ng...
Source
#1Giuseppe Grosso (University of Catania)H-Index: 64
Source
#1Clare Whitton (NUS: National University of Singapore)H-Index: 9
#2Yvonne Hui Min Wong (NUS: National University of Singapore)
Last. Rob M. van Dam (NUS: National University of Singapore)H-Index: 105
view all 3 authors...
Identifying when most weight gain occurs throughout the life course can inform targeted public health interventions. We evaluated the association of childbirth, marriage, and employment changes with weight changes in a multi-ethnic Asian cohort. Singapore Multi-Ethnic Cohort participants ≥21 years (n = 9655) who identified as ethnic Chinese, Malay, or Indian were weighed and interviewed about marital status, employment, and number of children at baseline and after about four years. We used multi...
Source
Regular physical activity (PA) is both a preventive measure and a cure for non-communicable diseases (NCDs) [...]
Source
#1Ricci Hannah (UCSD: University of California, San Diego)H-Index: 17
#2Sumitash Jana (UCSD: University of California, San Diego)H-Index: 5
Last. Vignesh Muralidharan (UCSD: University of California, San Diego)H-Index: 6
view all 3 authors...
Source
Abstract null null Drosophila is a valuable paradigm for studying tumorigenesis and cancer. Mutations causing hematopoietic aberrations and melanotic-blood-tumors found in Drosophila mutants are vastly studied. Clear understanding about the blood cells, signaling pathways and the tissues affected during hematopoietic tumor formation provide an opportunity to delineate the effects of cancer therapeutics. Using this simple hematopoietic archetype, we elucidated the effects of the anti-cancer drug,...
Source
#1Chih-Yu Hsu (Memorial Hospital of South Bend)H-Index: 1
#2Liang-Sien Chen (Memorial Hospital of South Bend)
Last. Hai-Hua Chuang (Memorial Hospital of South Bend)H-Index: 7
view all 8 authors...
Physical fitness (PF) is closely related to various health outcomes and quality of life among children. However, the associations between anthropometry, body composition (BC), and PF are not fully elucidated. This cross-sectional study aimed to investigate the associations between demographic metrics (age, sex), anthropometric measures (body mass index z-score (BMI z-score) waist/height ratio (WHtR)), BC parameters (body-fat percentage (BF%), muscle weight), and PF levels (800-m run, sit-and-rea...
Source