MiR-151b inhibits osteoblast differentiation via downregulating Msx2
Abstract
MicroRNA-151b (miR-151b) showed altered expression in ovariectomized rat model of osteoporosis. This study established an ovariectomy-induced osteoporotic rat model to investigate the role of miR-151b in osteoblasts.Eighteen female Sprague-Dawley (SD) rats were divided randomly into Sham and OVX group (n = 9). The transfections with different miRNAs and expression vectors were confirmed by RT-qPCR. The protein expression of Msx2 was detected by...
Paper Details
Title
MiR-151b inhibits osteoblast differentiation via downregulating Msx2
Published Date
Mar 10, 2021
Journal
Volume
63
Issue
2
Pages
112 - 123
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