In vivo CART cell imaging: Paving the way for success in CART cell therapy
Abstract
Chimeric antigen receptor T (CART) cells are a promising immunotherapy that has induced dramatic anti-tumor responses in certain B cell malignancies. However, CART cell expansion and trafficking are often insufficient to yield long-term remissions, and serious toxicities can arise after CART cell administration. Visualizing CART cell expansion and trafficking in patients can detect an inadequate CART cell response or serve as an early warning...
Paper Details
Title
In vivo CART cell imaging: Paving the way for success in CART cell therapy
Published Date
Mar 1, 2021
Volume
20
Pages
625 - 633
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