Exosome-functionalized polyetheretherketone-based implant with immunomodulatory property for enhancing osseointegration
Abstract
The host immune response effecting on biomaterials is critical to determine implant fates and bone regeneration property. Bone marrow stem cells (BMSCs) derived exosomes (Exos) contain multiple biosignal molecules and have been demonstrated to exhibit immunomodulatory functions. Herein, we develop a BMSC-derived Exos-functionalized implant to accelerate bone integration by immunoregulation. BMSC-derived Exos were reversibly incorporated on...
Paper Details
Title
Exosome-functionalized polyetheretherketone-based implant with immunomodulatory property for enhancing osseointegration
Published Date
Sep 1, 2021
Journal
Volume
6
Issue
9
Pages
2754 - 2766
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