MAGIs regulate aPKC to enable balanced distribution of intercellular tension for epithelial sheet homeostasis
Abstract
Constriction of the apical plasma membrane is a hallmark of epithelial cells that underlies cell shape changes in tissue morphogenesis and maintenance of tissue integrity in homeostasis. Contractile force is exerted by a cortical actomyosin network that is anchored to the plasma membrane by the apical junctional complexes (AJC). In this study, we present evidence that MAGI proteins, structural components of AJC whose function remained unclear,...
Paper Details
Title
MAGIs regulate aPKC to enable balanced distribution of intercellular tension for epithelial sheet homeostasis
Published Date
Mar 12, 2021
Journal
Volume
4
Issue
1
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History