Epigenetic and metabolic regulation of epidermal homeostasis
Abstract
Continuous exposure of the skin to environmental, mechanical and chemical stress necessitates constant self-renewal of the epidermis to maintain its barrier function. This self-renewal ability is attributed to epidermal stem cells (EPSCs), which are long-lived, multipotent cells located in the basal layer of the epidermis. Epidermal homeostasis - coordinated proliferation and differentiation of EPSCs - relies on fine-tuned adaptations in gene...
Paper Details
Title
Epigenetic and metabolic regulation of epidermal homeostasis
Published Date
Mar 10, 2021
Journal
Volume
30
Issue
8
Pages
1009 - 1022
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Notes
History