Cell size distribution of lineage data: Analytic results and parameter inference
Abstract
Recent advances in single-cell technologies have enabled time-resolved measurements of the cell size over several cell cycles. These data encode information on how cells correct size aberrations so that they do not grow abnormally large or small. Here, we formulate a piecewise deterministic Markov model describing the evolution of the cell size over many generations, for all three cell size homeostasis strategies (timer, sizer, and adder). The...
Paper Details
Title
Cell size distribution of lineage data: Analytic results and parameter inference
Published Date
Mar 1, 2021
Journal
Volume
24
Issue
3
Pages
102220 - 102220
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