Unattended Drug Discovery Screening Workflow in a 384-Well Automated Patch Clamp System

Automated patch clamp (APC) electrophysiology is an established and accepted technique in most safety testing laboratories. Recently published cross-site studies [1] highlight the need for standardized protocols for reliable results, for example, for Nav1.5 recordings. A standardization of protocols should be backed up by a robust screening assay before a screening workflow is implemented in a lab. Challenging state-of-the-art APC...