Control of oviductal fluid flow by the G-protein coupled receptor Adgrd1 is essential for murine embryo transit
Abstract
Dysfunction of embryo transport causes ectopic pregnancy which affects approximately 2% of conceptions in the US and Europe, and is the most common cause of pregnancy-related death in the first trimester. Embryo transit involves a valve-like tubal-locking phenomenon that temporarily arrests oocytes at the ampullary-isthmic junction (AIJ) where fertilisation occurs, but the mechanisms involved are unknown. Here we show that female mice lacking...
Paper Details
Title
Control of oviductal fluid flow by the G-protein coupled receptor Adgrd1 is essential for murine embryo transit
Published Date
Feb 23, 2021
Journal
Volume
12
Issue
1
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