PVT1: A long non-coding RNA recurrently involved in neoplasia-associated fusion transcripts
Abstract
NGS technologies and bioinformatics tools allow the rapid identification of chimeric transcripts in cancer. More than 40,000 fusions are so far reported in the literature; however, for most of them, the role in oncogenesis is still not fully understood. This is the case for fusions involving the long non-coding RNA (lncRNA) Plasmacytoma variant translocation 1 (PVT1) (8q24.21). This lncRNA displays oncogenic functions in several cancer types...
Paper Details
Title
PVT1: A long non-coding RNA recurrently involved in neoplasia-associated fusion transcripts
Published Date
May 1, 2021
Journal
Volume
779
Pages
145497 - 145497
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