Synaptophysin expression in mutated advanced colorectal cancers identifies a new subgroup of tumours with worse prognosis
Abstract
Background null Neuroendocrine differentiation has been extensively associated with worse prognosis and to mechanisms of therapy resistance in several epithelial cancers. A high prevalence of neuroendocrine differentiation was recently described in V600EBRAF-mutated (BRAFmt) metastatic colorectal cancers (mCRCs) but no data are available about its prognostic impact in this setting. null null null Methods null We assessed synaptophysin...
Paper Details
Title
Synaptophysin expression in mutated advanced colorectal cancers identifies a new subgroup of tumours with worse prognosis
Published Date
Mar 1, 2021
Journal
Volume
146
Pages
145 - 154
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Notes
History