Bioactive Apigenin loaded oral nano bilosomes: Formulation optimization to preclinical assessment
Abstract
Diabetic (type-2) is a metabolic disease characterized by increased blood glucose level from the normal level. In the present study, apigenin (AG) loaded lipid vesicles (bilosomes: BIL) was prepared, optimized and evaluated for the oral therapeutic efficacy.AG-BIL was prepared by a thin-film evaporation method using cholesterol, span 60 and sodium deoxycholate. The prepared formulation was optimized by 3-factor and 3-level Box-Behnken design...
Paper Details
Title
Bioactive Apigenin loaded oral nano bilosomes: Formulation optimization to preclinical assessment
Published Date
Mar 1, 2021
Journal
Volume
29
Issue
3
Pages
269 - 279
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