Does insulin resistance influence neurodegeneration in non-diabetic Alzheimer’s subjects?
Abstract
Background Type 2 diabetes is a risk factor for Alzheimer’s disease (AD), and AD brain shows impaired insulin signalling. The role of peripheral insulin resistance on AD aetiopathogenesis in non-diabetic patients is still debated. Here we evaluated the influence of insulin resistance on brain glucose metabolism, grey matter volume and white matter lesions (WMLs) in non-diabetic AD subjects. Methods In total, 130 non-diabetic AD subjects...
Paper Details
Title
Does insulin resistance influence neurodegeneration in non-diabetic Alzheimer’s subjects?
Published Date
Feb 17, 2021
Volume
13
Issue
1
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