Virtual clinical trial platforms for digital breast tomosynthesis: a local solution compared to the VICTRE platform

Aim: Compare an in-house developed hybrid simulation framework and the FDA’s total simulation framework VICTRE in an exercise to simulate realistic DBT images. Methods: Three different set-ups were investigated in increasing order of difficulty: (1) A simple object insert simulated in homogeneous backgrounds. (2) The same simple test object in a breast phantom to investigate the impact of a non-homogeneous background. (3) The simple test object...