Lack of Consistent Associations Between Pharmacologic Gastric Acid Suppression and Adverse Outcomes in Patients With Coronavirus Disease 2019: Meta-Analysis of Observational Studies

Coronavirus disease 2019 (COVID-19), a major healthcare problem of this century, has already claimed hundreds of thousands of lives. Rigorous research is examining potential therapeutic options. An early study reported that oral famotidine 80 mg 3 times a day was associated with improved patient-reported outcomes in nonhospitalized COVID-19 patients.1Janowitz T. et al.Gut. 2020; 69: 1592-1597Crossref PubMed Scopus (87) Google Scholar Since then,...