mTOR Signaling as a Regulator of Hematopoietic Stem Cell Fate

Volume: 17, Issue: 4, Pages: 1312 - 1322
Published: Feb 14, 2021
Abstract
Blood is generated throughout life by continued proliferation and differentiation of hematopoietic progenitors, while at the top of the hierarchy, hematopoietic stem cells (HSCs) remain largely quiescent. This way HSCs avoid senescence and preserve their capacity to repopulate the hematopoietic system. But HSCs are not always quiescent, proliferating extensively in conditions such as those found in the fetal liver. Understanding the elusive...
Paper Details
Title
mTOR Signaling as a Regulator of Hematopoietic Stem Cell Fate
Published Date
Feb 14, 2021
Volume
17
Issue
4
Pages
1312 - 1322
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