Impact of vitamin A transport and storage on intestinal retinoid homeostasis and functions
Abstract
Lecithin:retinol acyltransferase and retinol-binding protein enable vitamin A (VA) storage and transport, respectively, maintaining tissue homeostasis of retinoids (VA derivatives). The precarious VA status of the lecithin:retinol acyltransferase–deficient (Lrat−/−) retinol-binding protein–deficient (Rbp−/−) mice rapidly deteriorates upon dietary VA restriction, leading to signs of severe vitamin A deficiency (VAD). As retinoids impact gut...
Paper Details
Title
Impact of vitamin A transport and storage on intestinal retinoid homeostasis and functions
Published Date
Jan 1, 2021
Journal
Volume
62
Pages
100046 - 100046
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